The goal of this study was to compare the pharmacokinetics of nicardipine hydrochloride orally disintegrating tablets and β-cyclodextrin inclusion complex with its conventional tablets. Forty-five rats were divided into three groups evaluating the effect of dosage forms on the pharmacokinetics of nicardipine hydrochloride. Blood samples were taken at predefined sampling points 0–24h after medic...

---------------------------------------------------RECENT MAJOR CHANGES-------------------------------------------------­ Indications and Usage, Schizophrenia/Adolescents (1.1) 08/2007 Indications and Usage, Bipolar Mania/Pediatrics (1.2) 08/2007 Dosage and Administration, Schizophrenia/Adolescents (2.1) 08/2007 Dosage and Administration, Bipolar Mania/Pediatrics (2.2) 08/2007 -----------------...

Many orally disintegrating tablets have recently been developed to improve oral ingestion and usability and are widely administered clinically, resulting in improved quality of life for patients. Since orally disintegrating tablets rapidly disintegrate in the mouth, the masking of unpleasant taste is important. We investigated the masking of the taste of furosemide (FU) as a model drug with cor...

background: orally disintegrating tablets (odts) are a modern form of tablets that when placed in the oral cavity, disperses rapidly. these tablets have advantages, particularly good applications for children and old patients who have a complication in chewing or swallowing solid dosage forms. the aim of this study was to design, formulate, and evaluate the physicochemical properties of 5 mg mo...

Article history: Received on: 06/01/2014 Revised on: 22/01/2014 Accepted on: 12/02/2014 Available online: 27/02/2014 Orally disintegrating tablets (ODTs) have greatly increased dosage forms which have remarkable impact on the patient compliance especially for the pediatric, geriatric and psychiatric patients with deglutition disorders. Several technologies either conventional or patented based ...

orally disintegrating tablets (odt) have the advantages of both solid dosage form specially the stability and ease of handling and liquid dosage forms including ease of swallowing and pre-gastric absorption. we focused on taste masking and formulation of ranitidine odt which disintegrates rapidly in the mouth within 60 seconds using super-disintegrants, special polymers, water soluble and even ...

Risperidone is a white to slightly beige powder. It is practically insoluble in water, freely soluble in methylene chloride, and soluble in methanol and 0.1 N HCl. RISPERDAL® tablets are available in 0.25 mg (dark yellow), 0.5 mg (red-brown), 1 mg (white), 2 mg (orange), 3 mg (yellow), and 4 mg (green) strengths. Inactive ingredients are colloidal silicon dioxide, hypromellose, lactose, magnesi...

Its empirical formula is C15H19N5•C7H6O2, representing a molecular weight of the free base of 269.4. Rizatriptan benzoate is a white to off-white, crystalline solid that is soluble in water at about 42 mg per mL (expressed as free base) at 25°C. MAXALT Tablets and MAXALT-MLT* Orally Disintegrating Tablets are available for oral administration in strengths of 5 and 10 mg (corresponding to 7.265 ...